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24 Table 3 Estimated Sensitivity and Specificity of Serum Laboratory Tests for Vitamin B12 Deficiency Pernicious anemia refers to one of the hematologic manifestations of chronic auto-immune gastritis, in which the immune system targets the parietal cells of the stomach or intrinsic factor itself, leading to decreased absorption of vitamin B 12

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Here are some of the most common reasons for vitamin B12 deficiency: Pernicious Anemia This is the most common cause of vitamin B12 deficiency worldwide and mainly affects people of Northern European ancestry

The animals were first adapted to testing environment after a shortened pellet (10.3 cm), their usual diet, was administered in the cylinder